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Reduction-sensitive CD44 receptor-targeted hyaluronic acid derivative micelles for doxorubicin delivery

INTRODUCTION: A reduction-sensitive CD44-positive tumor-targetable drug delivery system for doxorubicin (DOX) delivery was developed based on hyaluronic acid (HA)-grafted polymers. MATERIALS AND METHODS: HA was conjugated with folic acid (FA) via a reduction-sensitive disulfide linkage to form an am...

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Bibliografski detalji
Izdano u:Int J Nanomedicine
Glavni autori: Yang, Yishun, Zhao, Yuan, Lan, Jinshuai, Kang, Yanan, Zhang, Tong, Ding, Yue, Zhang, Xinyu, Lu, Lu
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065576/
https://ncbi.nlm.nih.gov/pubmed/30100720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S165359
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