CD44-targeted pH-responsive micelles for enhanced cellular internalization and intracellular on-demand release of doxorubicin

Poor cellular uptake and slow intracellular drug release remain the main barriers for the efficient application of micellar delivery system. Taking advantage of the overexpressed CD44 receptor and mild acidic microenvironment of tumour cells, CD44-targeted pH-responsive micelles based on the self-as...

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Библиографические подробности
Главные авторы: Shudi Yang, Weiliang Chen, Wei Li, Jingcheng Song, Yue Gao, Xiaoping Li
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis Group 2021-01-01
Серии:Artificial Cells, Nanomedicine, and Biotechnology
Предметы:
CD44 targeted
pH responsive
micelles
doxorubicin
on-demand release
Online-ссылка:https://www.tandfonline.com/doi/10.1080/21691401.2021.1884085
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