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Update on Multiple Endocrine Neoplasia Type 2: Focus on Medullary Thyroid Carcinoma

Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant hereditary cancer syndrome caused by missense gain-of-function mutations in the RET proto-oncogene on chromosome 10. Specific RET mutations can predispose toward a particular phenotype and clinical course, with strong genotype–pheno...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Raue, Friedhelm, Frank-Raue, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065486/
https://ncbi.nlm.nih.gov/pubmed/30087948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2018-00178
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