LRIG2 promotes the proliferation and cell cycle progression of glioblastoma cells in vitro and in vivo through enhancing PDGFRβ signaling

The leucine-rich repeats and immunoglobulin-like domains (LRIG) gene family, comprising LRIG1, 2 and 3, encodes integral membrane proteins. It has been well established that LRIG1 negatively regulates multiple growth factor signaling pathways and is considered to be a tumor suppressor; however, the...

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Vydáno v:Int J Oncol
Hlavní autoři: Xiao, Qungen, Dong, Minhai, Cheng, Fangling, Mao, Feng, Zong, Weifeng, Wu, Kang, Wang, Heping, Xie, Ruifan, Wang, Baofeng, Lei, Ting, Guo, Dongsheng
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065455/
https://ncbi.nlm.nih.gov/pubmed/30015847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2018.4482
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