Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function

Nearly 100 loci have been identified for pulmonary function, almost exclusively in studies of European ancestry populations. We extend previous research by meta-analyzing genome-wide association studies of 1000 Genomes imputed variants in relation to pulmonary function in a multiethnic population of...

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Publicado no:Nat Commun
Main Authors: Wyss, Annah B., Sofer, Tamar, Lee, Mi Kyeong, Terzikhan, Natalie, Nguyen, Jennifer N., Lahousse, Lies, Latourelle, Jeanne C., Smith, Albert Vernon, Bartz, Traci M., Feitosa, Mary F., Gao, Wei, Ahluwalia, Tarunveer S., Tang, Wenbo, Oldmeadow, Christopher, Duan, Qing, de Jong, Kim, Wojczynski, Mary K., Wang, Xin-Qun, Noordam, Raymond, Hartwig, Fernando Pires, Jackson, Victoria E., Wang, Tianyuan, Obeidat, Ma’en, Hobbs, Brian D., Huan, Tianxiao, Gui, Hongsheng, Parker, Margaret M., Hu, Donglei, Mogil, Lauren S., Kichaev, Gleb, Jin, Jianping, Graff, Mariaelisa, Harris, Tamara B., Kalhan, Ravi, Heckbert, Susan R., Paternoster, Lavinia, Burkart, Kristin M., Liu, Yongmei, Holliday, Elizabeth G., Wilson, James G., Vonk, Judith M., Sanders, Jason L., Barr, R. Graham, de Mutsert, Renée, Menezes, Ana Maria Baptista, Adams, Hieab H. H., van den Berge, Maarten, Joehanes, Roby, Levin, Albert M., Liberto, Jennifer, Launer, Lenore J., Morrison, Alanna C., Sitlani, Colleen M., Celedón, Juan C., Kritchevsky, Stephen B., Scott, Rodney J., Christensen, Kaare, Rotter, Jerome I., Bonten, Tobias N., Wehrmeister, Fernando César, Bossé, Yohan, Xiao, Shujie, Oh, Sam, Franceschini, Nora, Brody, Jennifer A., Kaplan, Robert C., Lohman, Kurt, McEvoy, Mark, Province, Michael A., Rosendaal, Frits R., Taylor, Kent D., Nickle, David C., Williams, L. Keoki, Burchard, Esteban G., Wheeler, Heather E., Sin, Don D., Gudnason, Vilmundur, North, Kari E., Fornage, Myriam, Psaty, Bruce M., Myers, Richard H., O’Connor, George, Hansen, Torben, Laurie, Cathy C., Cassano, Patricia A., Sung, Joohon, Kim, Woo Jin, Attia, John R., Lange, Leslie, Boezen, H. Marike, Thyagarajan, Bharat, Rich, Stephen S., Mook-Kanamori, Dennis O., Horta, Bernardo Lessa, Uitterlinden, André G., Im, Hae Kyung, Cho, Michael H., Brusselle, Guy G., Gharib, Sina A., Dupuis, Josée, Manichaikul, Ani, London, Stephanie J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065313/
https://ncbi.nlm.nih.gov/pubmed/30061609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05369-0
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