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Significance of clonal mutations in bone marrow failure and inherited MDS/AML predisposition syndromes
Clonal hematopoiesis as a hallmark of myelodysplastic syndrome (MDS) is mediated by the selective advantage of clonal hematopoietic stem cells in a context-specific manner. While primary MDS emerges without known predisposing cause and is associated with advanced age, secondary MDS may develop in yo...
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| 發表在: | Hematol Oncol Clin North Am |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6065266/ https://ncbi.nlm.nih.gov/pubmed/30047417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2018.03.005 |
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