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Significance of clonal mutations in bone marrow failure and inherited MDS/AML predisposition syndromes

Clonal hematopoiesis as a hallmark of myelodysplastic syndrome (MDS) is mediated by the selective advantage of clonal hematopoietic stem cells in a context-specific manner. While primary MDS emerges without known predisposing cause and is associated with advanced age, secondary MDS may develop in yo...

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Xehetasun bibliografikoak
Argitaratua izan da:Hematol Oncol Clin North Am
Egile Nagusiak: Schaefer, Eva J., Lindsley, R. Coleman
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065266/
https://ncbi.nlm.nih.gov/pubmed/30047417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2018.03.005
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