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Conformational changes allow processing of bulky substrates by a haloalkane dehalogenase with a small and buried active site
Haloalkane dehalogenases catalyze the hydrolysis of halogen–carbon bonds in organic halogenated compounds and as such are of great utility as biocatalysts. The crystal structures of the haloalkane dehalogenase DhlA from the bacterium from Xanthobacter autotrophicus GJ10, specifically adapted for the...
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| 發表在: | J Biol Chem |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6065182/ https://ncbi.nlm.nih.gov/pubmed/29858243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000328 |
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