Tempol Protects Against Acute Renal Injury by Regulating PI3K/Akt/mTOR and GSK3β Signaling Cascades and Afferent Arteriolar Activity

BACKGROUND/AIMS: Free radical scavenger tempol is a protective antioxidant against ischemic injury. Tubular epithelial apoptosis is one of the main changes in the renal ischemia/reperfusion (I/R) injury. Meanwhile some proteins related with apoptosis and inflammation are also involved in renal I/R i...

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Publicado en:Kidney Blood Press Res
Autores principales: Zhang, Gensheng, Wang, Qin, Wang, Wenwen, Yu, Minghua, Zhang, Suping, Xu, Nan, Zhou, Suhan, Cao, Xiaoyun, Fu, Xiaodong, Ma, Zufu, Liu, Ruisheng, Mao, Jianhua, Lai, En Yin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065105/
https://ncbi.nlm.nih.gov/pubmed/29870982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000490338
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