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Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons
Neocortical pyramidal neurons express several distinct subtypes of voltage-gated Na(+) channels. In mature cells, Na(v)1.6 is the dominant channel subtype in the axon initial segment (AIS) as well as in the nodes of Ranvier. Action potentials (APs) are initiated in the AIS, and it has been proposed...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6065046/ https://ncbi.nlm.nih.gov/pubmed/29991598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1720493115 |
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