Out-of-the-groove transport of lipids by TMEM16 and GPCR scramblases

Phospholipid scramblases externalize phosphatidylserine to facilitate numerous physiological processes. Several members of the structurally unrelated TMEM16 and G protein-coupled receptor (GPCR) protein families mediate phospholipid scrambling. The structure of a TMEM16 scramblase shows a membrane-e...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Malvezzi, Mattia, Andra, Kiran K., Pandey, Kalpana, Lee, Byoung-Cheol, Falzone, Maria E., Brown, Ashley, Iqbal, Rabia, Menon, Anant K., Accardi, Alessio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2018
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PNAS Plus
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6065010/
https://ncbi.nlm.nih.gov/pubmed/29925604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1806721115
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