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Feasibility and biological rationale of repurposing sunitinib and erlotinib for dengue treatment

There is an urgent need for strategies to combat dengue virus (DENV) infection; a major global threat. We reported that the cellular kinases AAK1 and GAK regulate intracellular trafficking of multiple viruses and that sunitinib and erlotinib, approved anticancer drugs with potent activity against th...

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Bibliographic Details
Published in:Antiviral Res
Main Authors: Pu, Szuyuan, Xiao, Fei, Schor, Stanford, Bekerman, Elena, Zanini, Fabio, Barouch-Bentov, Rina, Nagamine, Claude M., Einav, Shirit
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6064211/
https://ncbi.nlm.nih.gov/pubmed/29753658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2018.05.001
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