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Cognitive and emotional alterations in App knock-in mouse models of Aβ amyloidosis
BACKGROUND: Alzheimer’s disease (AD), the most common cause of dementia, is characterized by the progressive deposition of amyloid-β (Aβ) peptides and neurofibrillary tangles. Mouse models of Aβ amyloidosis generated by knock-in (KI) of a humanized Aβ sequence provide distinct advantages over tradit...
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| Pubblicato in: | BMC Neurosci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6064053/ https://ncbi.nlm.nih.gov/pubmed/30055565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-018-0446-8 |
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