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Long-term Rescue of Photoreceptors in a Rodent Model of Retinitis Pigmentosa Associated with MERTK Mutation

MERTK mutation reduces the ability of retinal pigment epithelial (RPE) cells to phagocytize the photoreceptor outer segments, which leads to accumulation of debris separating photoreceptors from RPE cells, resulting in their degeneration and loss of vision. In a rat model of Retinitis Pigmentosa due...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lorach, H., Kang, S., Dalal, R., Bhuckory, M. B., Quan, Y., Palanker, D.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063887/
https://ncbi.nlm.nih.gov/pubmed/30054542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29631-z
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