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Soft Substrates Containing Hyaluronan Mimic the Effects of Increased Stiffness on Morphology, Motility, and Proliferation of Glioma Cells

Unlike many other cancer cells that grow in tumors characterized by an abnormally stiff collagen-enriched stroma, glioma cells proliferate and migrate in the much softer environment of the brain, which generally lacks the filamentous protein matrix characteristic of breast, liver, colorectal, and ot...

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Detalhes bibliográficos
Publicado no:Biomacromolecules
Main Authors: Pogoda, Katarzyna, Bucki, Robert, Byfield, Fitzroy J., Cruz, Katrina, Lee, Tongkeun, Marcinkiewicz, Cezary, Janmey, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063754/
https://ncbi.nlm.nih.gov/pubmed/28858529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.7b00324
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