TNF overproduction impairs epithelial staphylococcal response in hyper IgE syndrome

Autosomal dominant hyper IgE syndrome (AD-HIES), or Job’s syndrome, is a primary immune deficiency caused by dominant-negative mutations in STAT3. Recurrent Staphylococcus aureus skin abscesses are a defining feature of this syndrome. A widely held hypothesis that defects in peripheral Th17 differen...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Myles, Ian A., Anderson, Erik D., Earland, Noah J., Zarember, Kol A., Sastalla, Inka, Williams, Kelli W., Gough, Portia, Moore, Ian N., Ganesan, Sundar, Fowler, Cedar J., Laurence, Arian, Garofalo, Mary, Kuhns, Douglas B., Kieh, Mark D., Saleem, Arhum, Welch, Pamela A., Darnell, Dirk A., Gallin, John I., Freeman, Alexandra F., Holland, Steven M., Datta, Sandip K.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063472/
https://ncbi.nlm.nih.gov/pubmed/30035749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121486
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker