טוען...

Eupatilin rescues ciliary transition zone defects to ameliorate ciliopathy-related phenotypes

Ciliopathies are clinically overlapping genetic disorders involving structural and functional abnormalities of cilia. Currently, there are no small-molecule drugs available to treat ciliary defects in ciliopathies. Our phenotype-based screen identified the flavonoid eupatilin and its analogs as lead...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Clin Invest
Main Authors: Kim, Yong Joon, Kim, Sungsoo, Jung, Yooju, Jung, Eunji, Kwon, Ho Jeong, Kim, Joon
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063470/
https://ncbi.nlm.nih.gov/pubmed/30035750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99232
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!