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Kappa opioid receptor antagonism: Are opioids the answer for treatment resistant depression?

INTRODUCTION: Past trials of buprenorphine (BUP) in the treatment of major depressive disorder (MDD) have displayed favorable results, although its clinical utility was limited by the risk of abuse or physical dependence. By combining BUP with samidorphan (SAM), the euphoric high is negated by an op...

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Detalhes bibliográficos
Publicado no:Ment Health Clin
Main Authors: Peckham, Alyssa M., De La Cruz, Austin, Dufresne, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: College of Psychiatric & Neurologic Pharmacists 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063454/
https://ncbi.nlm.nih.gov/pubmed/30155392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.9740/mhc.2018.07.175
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