Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells

The treatment of acute promyelocytic leukemia (APL) with all-trans retinoic acid (ATRA) induces granulocytic differentiation. This process renders APL cells resistant to cytotoxic chemotherapies. Epigenetic regulators of the histone deacetylases (HDACs) family, which comprise four classes (I–IV), cr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Arch Toxicol
Egile Nagusiak: Noack, Katrin, Mahendrarajah, Nisintha, Hennig, Dorle, Schmidt, Luisa, Grebien, Florian, Hildebrand, Dagmar, Christmann, Markus, Kaina, Bernd, Sellmer, Andreas, Mahboobi, Siavosh, Kubatzky, Katharina, Heinzel, Thorsten, Krämer, Oliver H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063353/
https://ncbi.nlm.nih.gov/pubmed/27807597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1878-5
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