Analysis of the interplay between all-trans retinoic acid and histone deacetylase inhibitors in leukemic cells

The treatment of acute promyelocytic leukemia (APL) with all-trans retinoic acid (ATRA) induces granulocytic differentiation. This process renders APL cells resistant to cytotoxic chemotherapies. Epigenetic regulators of the histone deacetylases (HDACs) family, which comprise four classes (I–IV), cr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Noack, Katrin, Mahendrarajah, Nisintha, Hennig, Dorle, Schmidt, Luisa, Grebien, Florian, Hildebrand, Dagmar, Christmann, Markus, Kaina, Bernd, Sellmer, Andreas, Mahboobi, Siavosh, Kubatzky, Katharina, Heinzel, Thorsten, Krämer, Oliver H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6063353/
https://ncbi.nlm.nih.gov/pubmed/27807597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1878-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados