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Betaine reduces β-amyloid-induced paralysis through activation of cystathionine-β-synthase in an Alzheimer model of Caenorhabditis elegans

BACKGROUND: The neurodegenerative disorder Alzheimer’s disease is caused by the accumulation of toxic aggregates of β-amyloid in the human brain. On the one hand, hyperhomocysteinemia has been shown to be a risk factor for cognitive decline in Alzheimer’s disease. On the other hand, betaine has been...

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Bibliographic Details
Published in:Genes Nutr
Main Authors: Leiteritz, Anne, Dilberger, Benjamin, Wenzel, Uwe, Fitzenberger, Elena
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062997/
https://ncbi.nlm.nih.gov/pubmed/30065790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12263-018-0611-9
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