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Four key steps control glycolytic flux in mammalian cells

Altered glycolysis is a hallmark of diseases including diabetes and cancer. Despite intensive study of the contributions of individual glycolytic enzymes, systems-level analyses of flux control through glycolysis remain limited. Here, we overexpress in two mammalian cell lines the individual enzymes...

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Detalhes bibliográficos
Publicado no:Cell Syst
Main Authors: Tanner, Lukas Bahati, Goglia, Alexander G., Wei, Monica H., Sehgal, Talen, Parsons, Lance R., Park, Junyoung O., White, Eileen, Toettcher, Jared E., Rabinowitz, Joshua D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062487/
https://ncbi.nlm.nih.gov/pubmed/29960885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.06.003
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