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Dissecting FcγR Regulation Through a Multivalent Binding Model

Many immune receptors transduce activation across the plasma membrane through their clustering. With Fcγ receptors, this clustering is driven by binding to antibodies of differing affinities that are in turn bound to multivalent antigen. As a consequence of this activation mechanism, accounting for...

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Publicado en:Cell Syst
Autores principales: Robinett, Ryan A., Guan, Ning, Lux, Anja, Biburger, Markus, Nimmerjahn, Falk, Meyer, Aaron S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062446/
https://ncbi.nlm.nih.gov/pubmed/29960887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2018.05.018
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