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Mechanistic understanding of molecular initiating events (MIEs) using NMR spectroscopy

Toxicological risk assessments in the 21(st) century are increasingly being driven by the Adverse Outcome Pathways (AOP) conceptual framework in which the Molecular Initiating Event (MIE) is of fundamental importance to pathway progression. For those MIEs that involve covalent chemical reactions, su...

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Опубликовано в: :Toxicol Res (Camb)
Главные авторы: Sanderson, Paul N., Simpson, Wendy, Cubberley, Richard, Aleksic, Maja, Gutsell, Stephen, Russell, Paul J.
Формат: Artigo
Язык:Inglês
Опубликовано: Royal Society of Chemistry 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062258/
https://ncbi.nlm.nih.gov/pubmed/30090324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00246j
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