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Mechanistic understanding of molecular initiating events (MIEs) using NMR spectroscopy

Toxicological risk assessments in the 21(st) century are increasingly being driven by the Adverse Outcome Pathways (AOP) conceptual framework in which the Molecular Initiating Event (MIE) is of fundamental importance to pathway progression. For those MIEs that involve covalent chemical reactions, su...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Main Authors: Sanderson, Paul N., Simpson, Wendy, Cubberley, Richard, Aleksic, Maja, Gutsell, Stephen, Russell, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062258/
https://ncbi.nlm.nih.gov/pubmed/30090324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00246j
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