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Comparison of Targeted Maximum Likelihood and Shrinkage Estimators of Parameters in Gene Networks

Gene regulatory networks, in which edges between nodes describe interactions between transcription factors (TFs) and their target genes, model regulatory interactions that determine the cell-type and condition-specific expression of genes. Regression methods can be used to identify TF-target gene in...

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Veröffentlicht in:Stat Appl Genet Mol Biol
Hauptverfasser: Geeven, Geert, van der Laan, Mark J., de Gunst, Mathisca C.M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061945/
https://ncbi.nlm.nih.gov/pubmed/23023699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/1544-6115.1728
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