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Comparison of Targeted Maximum Likelihood and Shrinkage Estimators of Parameters in Gene Networks

Gene regulatory networks, in which edges between nodes describe interactions between transcription factors (TFs) and their target genes, model regulatory interactions that determine the cell-type and condition-specific expression of genes. Regression methods can be used to identify TF-target gene in...

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Pubblicato in:Stat Appl Genet Mol Biol
Autori principali: Geeven, Geert, van der Laan, Mark J., de Gunst, Mathisca C.M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061945/
https://ncbi.nlm.nih.gov/pubmed/23023699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/1544-6115.1728
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