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Comparison of Targeted Maximum Likelihood and Shrinkage Estimators of Parameters in Gene Networks

Gene regulatory networks, in which edges between nodes describe interactions between transcription factors (TFs) and their target genes, model regulatory interactions that determine the cell-type and condition-specific expression of genes. Regression methods can be used to identify TF-target gene in...

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Publicat a:Stat Appl Genet Mol Biol
Autors principals: Geeven, Geert, van der Laan, Mark J., de Gunst, Mathisca C.M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061945/
https://ncbi.nlm.nih.gov/pubmed/23023699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/1544-6115.1728
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