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An Integrated Genome Wide CRISPRa Approach to Functionalize IncRNAs in Drug Resistance
Resistance to chemotherapy plays a significant role in cancer mortality. To identify genetic units affecting sensitivity to cytarabine, the mainstay of treatment for AML, we developed a comprehensive and integrated genome wide platform based on a Dual protein-coding and noncoding Integrated CRISPRa...
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| 發表在: | Cell |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6061940/ https://ncbi.nlm.nih.gov/pubmed/29677511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.03.052 |
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