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Circular permutation profiling by deep sequencing libraries created using transposon mutagenesis
Deep mutational scanning has been used to create high-resolution DNA sequence maps that illustrate the functional consequences of large numbers of point mutations. However, this approach has not yet been applied to libraries of genes created by random circular permutation, an engineering strategy th...
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| Gepubliceerd in: | Nucleic Acids Res |
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| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2018
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6061844/ https://ncbi.nlm.nih.gov/pubmed/29912470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky255 |
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