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Structural motifs in eIF4G and 4E-BPs modulate their binding to eIF4E to regulate translation initiation in yeast

The interaction of the eukaryotic initiation factor 4G (eIF4G) with the cap-binding protein eIF4E initiates cap-dependent translation and is regulated by the 4E-binding proteins (4E-BPs), which compete with eIF4G to repress translation. Metazoan eIF4G and 4E-BPs interact with eIF4E via canonical and...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Grüner, Stefan, Weber, Ramona, Peter, Daniel, Chung, Min-Yi, Igreja, Cátia, Valkov, Eugene, Izaurralde, Elisa
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061780/
https://ncbi.nlm.nih.gov/pubmed/30053226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky542
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