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A randomised Phase II/III study to evaluate the efficacy and safety of orally administered Oxalobacter formigenes to treat primary hyperoxaluria

Primary hyperoxaluria (PH) patients overproduce oxalate because of rare genetic errors in glyoxylate metabolism. Recurrent urolithiasis and/or progressive nephrocalcinosis are PH hallmarks and can lead to kidney damage, systemic oxalosis and death. Based on previous studies, we hypothesised that tre...

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Detalhes bibliográficos
Publicado no:Urolithiasis
Principais autores: Milliner, Dawn, Hoppe, Bernd, Groothoff, Jaap
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061479/
https://ncbi.nlm.nih.gov/pubmed/28718073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00240-017-0998-6
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