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A randomised Phase II/III study to evaluate the efficacy and safety of orally administered Oxalobacter formigenes to treat primary hyperoxaluria

Primary hyperoxaluria (PH) patients overproduce oxalate because of rare genetic errors in glyoxylate metabolism. Recurrent urolithiasis and/or progressive nephrocalcinosis are PH hallmarks and can lead to kidney damage, systemic oxalosis and death. Based on previous studies, we hypothesised that tre...

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Vydáno v:Urolithiasis
Hlavní autoři: Milliner, Dawn, Hoppe, Bernd, Groothoff, Jaap
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061479/
https://ncbi.nlm.nih.gov/pubmed/28718073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00240-017-0998-6
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