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Screening for human urinary bladder carcinogens: two-year bioassay is unnecessary

Screening for carcinogens in general, and for the urinary bladder specifically, traditionally involves a two-year bioassay in rodents, the results of which often do not have direct relevance to humans with respect to mode of action (MOA) and/or dose response. My proposal describes a multi-step short...

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Detalhes bibliográficos
Publicado no:Toxicol Res (Camb)
Autor principal: Cohen, Samuel M.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061447/
https://ncbi.nlm.nih.gov/pubmed/30090607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7tx00294g
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