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Critical role of toxicologic pathology in a short-term screen for carcinogenicity

Carcinogenic potential of chemicals is currently evaluated using a two year bioassay in rodents. Numerous difficulties are known for this assay, most notably, the lack of information regarding detailed dose response and human relevance of any positive findings. A screen for carcinogenic activity has...

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Bibliografische gegevens
Gepubliceerd in:J Toxicol Pathol
Hoofdauteurs: Cohen, Samuel M., Arnold, Lora L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Japanese Society of Toxicologic Pathology 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097964/
https://ncbi.nlm.nih.gov/pubmed/27821906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2016-0036
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