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The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice

AIMS/HYPOTHESIS: Dipeptidyl peptidase 4 (DPP-4) inhibitors are agents designed to increase the half-life of incretins. Although they are administered orally, little is known about their effects on the gut microbiota and functions, despite the fact that some bacteria present in the gut microbiota exh...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Olivares, Marta, Neyrinck, Audrey M., Pötgens, Sarah A., Beaumont, Martin, Salazar, Nuria, Cani, Patrice D., Bindels, Laure B., Delzenne, Nathalie M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061172/
https://ncbi.nlm.nih.gov/pubmed/29797022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4647-6
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