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The DPP-4 inhibitor vildagliptin impacts the gut microbiota and prevents disruption of intestinal homeostasis induced by a Western diet in mice

AIMS/HYPOTHESIS: Dipeptidyl peptidase 4 (DPP-4) inhibitors are agents designed to increase the half-life of incretins. Although they are administered orally, little is known about their effects on the gut microbiota and functions, despite the fact that some bacteria present in the gut microbiota exh...

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Dades bibliogràfiques
Publicat a:Diabetologia
Autors principals: Olivares, Marta, Neyrinck, Audrey M., Pötgens, Sarah A., Beaumont, Martin, Salazar, Nuria, Cani, Patrice D., Bindels, Laure B., Delzenne, Nathalie M.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6061172/
https://ncbi.nlm.nih.gov/pubmed/29797022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-018-4647-6
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