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Reduced and optimized trial designs for drugs described by a target mediated drug disposition model
Monoclonal antibodies against soluble targets are often rich and include the sampling of multiple analytes over a lengthy period of time. Predictive models built on data obtained in such studies can be useful in all drug development phases. If adequate model predictions can be maintained with a redu...
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| Publié dans: | J Pharmacokinet Pharmacodyn |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer US
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6061097/ https://ncbi.nlm.nih.gov/pubmed/29948794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10928-018-9594-9 |
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