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Expanding complement therapeutics for the treatment of paroxysmal nocturnal hemoglobinuria
Paroxysmal nocturnal hemoglobinuria (PNH) is widely regarded as an archetypal complement-mediated disorder that has propelled complement drug discovery in recent decades. Its pathology is driven by chronic complement dysregulation resulting from the lack of the GPI-linked regulators DAF and CD59 on...
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| Publicado no: | Semin Hematol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6060635/ https://ncbi.nlm.nih.gov/pubmed/30032754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2018.02.002 |
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