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Complement in paroxysmal nocturnal hemoglobinuria: exploiting our current knowledge to improve the treatment landscape
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematological disorder associated with an acquired deficiency in glycophosphatidylinositol-anchor biosynthesis that renders erythrocytes susceptible to complement attack. Intravascular hemolysis via the membrane attack complex is a clinical hallmar...
Shranjeno v:
| izdano v: | Expert Rev Hematol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4383744/ https://ncbi.nlm.nih.gov/pubmed/25213458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/17474086.2014.953926 |
| Oznake: |
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