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Complement in paroxysmal nocturnal hemoglobinuria: exploiting our current knowledge to improve the treatment landscape
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare hematological disorder associated with an acquired deficiency in glycophosphatidylinositol-anchor biosynthesis that renders erythrocytes susceptible to complement attack. Intravascular hemolysis via the membrane attack complex is a clinical hallmar...
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| 出版年: | Expert Rev Hematol |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4383744/ https://ncbi.nlm.nih.gov/pubmed/25213458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/17474086.2014.953926 |
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