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Checkpoint Blockade Rescues the Repressive Effect of Histone Deacetylases Inhibitors on γδ T Cell Function

Histone deacetylases (HDAC) are one of the key epigenetic modifiers that control chromatin accessibility and gene expression. Their role in tumorigenesis is well established and HDAC inhibitors have emerged as an effective treatment modality. HDAC inhibitors have been investigated for their specific...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bhat, Sajad A., Vedpathak, Disha Mohan, Chiplunkar, Shubhada V.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060239/
https://ncbi.nlm.nih.gov/pubmed/30072989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01615
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