Activated platelets induce MLKL-driven neutrophil necroptosis and release of neutrophil extracellular traps in venous thrombosis

Venous thromboembolic (VTE) disease, often manifesting as deep vein thrombosis or pulmonary embolism, involves clot formation consisting of blood cells and platelets locked in plasma protein and chromatin networks. The latter derives from neutrophil extracellular traps released by dying neutrophils;...

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Vydáno v:Cell Death Discov
Hlavní autoři: Nakazawa, Daigo, Desai, Jyaysi, Steiger, Stefanie, Müller, Susanne, Devarapu, Satish Kumar, Mulay, Shrikant R., Iwakura, Takamasa, Anders, Hans-Joachim
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060161/
https://ncbi.nlm.nih.gov/pubmed/30062055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0073-2
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