Activated platelets induce MLKL-driven neutrophil necroptosis and release of neutrophil extracellular traps in venous thrombosis

Venous thromboembolic (VTE) disease, often manifesting as deep vein thrombosis or pulmonary embolism, involves clot formation consisting of blood cells and platelets locked in plasma protein and chromatin networks. The latter derives from neutrophil extracellular traps released by dying neutrophils;...

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Bibliographic Details
Published in:Cell Death Discov
Main Authors: Nakazawa, Daigo, Desai, Jyaysi, Steiger, Stefanie, Müller, Susanne, Devarapu, Satish Kumar, Mulay, Shrikant R., Iwakura, Takamasa, Anders, Hans-Joachim
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060161/
https://ncbi.nlm.nih.gov/pubmed/30062055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-018-0073-2
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