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Metabolomic analysis of mouse prefrontal cortex reveals upregulated analytes during wakefulness compared to sleep

By identifying endogenous molecules in brain extracellular fluid metabolomics can provide insight into the regulatory mechanisms and functions of sleep. Here we studied how the cortical metabolome changes during sleep, sleep deprivation and spontaneous wakefulness. Mice were implanted with electrode...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bourdon, Allen K., Spano, Giovanna Maria, Marshall, William, Bellesi, Michele, Tononi, Giulio, Serra, Pier Andrea, Baghdoyan, Helen A., Lydic, Ralph, Campagna, Shawn R., Cirelli, Chiara
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060152/
https://ncbi.nlm.nih.gov/pubmed/30046159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29511-6
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