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Metabolomic analysis of mouse prefrontal cortex reveals upregulated analytes during wakefulness compared to sleep

By identifying endogenous molecules in brain extracellular fluid metabolomics can provide insight into the regulatory mechanisms and functions of sleep. Here we studied how the cortical metabolome changes during sleep, sleep deprivation and spontaneous wakefulness. Mice were implanted with electrode...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Bourdon, Allen K., Spano, Giovanna Maria, Marshall, William, Bellesi, Michele, Tononi, Giulio, Serra, Pier Andrea, Baghdoyan, Helen A., Lydic, Ralph, Campagna, Shawn R., Cirelli, Chiara
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060152/
https://ncbi.nlm.nih.gov/pubmed/30046159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29511-6
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