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Metabolomic analysis of mouse prefrontal cortex reveals upregulated analytes during wakefulness compared to sleep

By identifying endogenous molecules in brain extracellular fluid metabolomics can provide insight into the regulatory mechanisms and functions of sleep. Here we studied how the cortical metabolome changes during sleep, sleep deprivation and spontaneous wakefulness. Mice were implanted with electrode...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Bourdon, Allen K., Spano, Giovanna Maria, Marshall, William, Bellesi, Michele, Tononi, Giulio, Serra, Pier Andrea, Baghdoyan, Helen A., Lydic, Ralph, Campagna, Shawn R., Cirelli, Chiara
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6060152/
https://ncbi.nlm.nih.gov/pubmed/30046159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29511-6
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