Cross-species systems analysis identifies gene networks differentially altered by sleep loss and depression

To understand the transcriptomic organization underlying sleep and affective function, we studied a population of (C57BL/6J × 129S1/SvImJ) F2 mice by measuring 283 affective and sleep phenotypes and profiling gene expression across four brain regions. We identified converging molecular bases for sle...

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Détails bibliographiques
Publié dans:Sci Adv
Auteurs principaux: Scarpa, Joseph R., Jiang, Peng, Gao, Vance D., Fitzpatrick, Karrie, Millstein, Joshua, Olker, Christopher, Gotter, Anthony, Winrow, Christopher J., Renger, John J., Kasarskis, Andrew, Turek, Fred W., Vitaterna, Martha H.
Format: Artigo
Langue:Inglês
Publié: American Association for the Advancement of Science 2018
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059761/
https://ncbi.nlm.nih.gov/pubmed/30050989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat1294
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