βKlotho inhibits androgen/androgen receptor-associated epithelial-mesenchymal transition in prostate cancer through inactivation of ERK1/2 signaling

The epithelial-mesenchymal transition (EMT) is reported to have intimate crosstalk with androgen receptor (AR) signaling in prostate cancer (PCa) and is known to be responsible for castration resistance. Fibroblast growth factor/receptor (FGF/FGFR) signaling is also involved in tumor progression and...

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Pubblicato in:Oncol Rep
Autori principali: Liu, Zhao, Zhang, Hui, Ding, Sentai, Qi, Shasha, Liu, Shuai, Sun, Dingqi, Dong, Wei, Yin, Lei, Li, Mingjiang, Zhao, Xingbo, Lu, Jiaju
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2018
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059743/
https://ncbi.nlm.nih.gov/pubmed/29749458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2018.6399
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