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Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics
Given the increasing incidence of antibiotic resistance, antibiotics that employ new strategies are urgently needed. Bacterial survival is dependent on proper function of the signal recognition particle (SRP) and its receptor (FtsY). A unique set of interactions in FtsY:SRP-RNA represents a promisin...
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| 發表在: | PLoS One |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6059433/ https://ncbi.nlm.nih.gov/pubmed/30044812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200387 |
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