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Discovery of fragments that target key interactions in the signal recognition particle (SRP) as potential leads for a new class of antibiotics
Given the increasing incidence of antibiotic resistance, antibiotics that employ new strategies are urgently needed. Bacterial survival is dependent on proper function of the signal recognition particle (SRP) and its receptor (FtsY). A unique set of interactions in FtsY:SRP-RNA represents a promisin...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6059433/ https://ncbi.nlm.nih.gov/pubmed/30044812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200387 |
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