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Proteasome inhibition attenuates rasfonin-induced autophagy concurring with the upregulation of caspase-dependent apoptosis

Two major protein quality control mechanisms exist in eukaryotic cells, the ubiquitin-proteasome system (UPS) and the autophagy–lysosome system. Generally, the inhibition of UPS is believed to enhance autophagic pathway; nevertheless, the crosstalk between these two degradation systems may be much m...

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Detalhes bibliográficos
Publicado no:Mycology
Main Authors: Yan, Siyuan, Che, Yongsheng, Jiang, Xuejun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059125/
https://ncbi.nlm.nih.gov/pubmed/30123613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21501203.2016.1147091
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