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Comparison of NMR and Dynamic Light Scattering for Measuring Diffusion Coefficients of Formulated Insulin: Implications for Particle Size Distribution Measurements in Drug Products

Particle size distribution, a measurable physicochemical quantity, is a critical quality attribute of drug products that needs to be controlled in drug manufacturing. The non-invasive methods of dynamic light scattering (DLS) and Diffusion Ordered SpectroscopY (DOSY) NMR can be used to measure diffu...

詳細記述

保存先:
書誌詳細
出版年:AAPS J
主要な著者: Patil, Sharadrao M., Keire, David A., Chen, Kang
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058974/
https://ncbi.nlm.nih.gov/pubmed/28791599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-017-0127-z
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