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Gastroretentive raft liquid delivery system as a new approach to release extension for carrier-mediated drug
Gabapentin (GBP), an antiepileptic and anti-neuropathic agent, suffers from short half-life (5–7 h), has narrow absorption window, and is absorbed via carrier-mediated mechanism resulting in frequent dosing, poor compliance, and poor bioavailability (<60%). Moreover, GBP is a freely water-soluble...
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| Publicado no: | Drug Deliv |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6058684/ https://ncbi.nlm.nih.gov/pubmed/29792353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1474969 |
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