Licorice root extract and magnesium isoglycyrrhizinate protect against triptolide-induced hepatotoxicity via up-regulation of the Nrf2 pathway

Triptolide, the predominant biologically active component of the Chinese herb Tripterygium wilfordii Hook f., possesses numerous pharmacological activities, including anti-inflammatory, anti-fertility, anti-neoplastic, and immunosuppressive effects. However, toxicity and severe adverse effects, part...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Deliv
Hauptverfasser: Tan, Qin-You, Hu, Qian, Zhu, Sheng-Nan, Jia, Lu-Lu, Xiao, Juan, Su, Hua-Zhen, Huang, Shao-Yuan, Zhang, Jing, Jin, Junfei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058668/
https://ncbi.nlm.nih.gov/pubmed/29791258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1472676
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