Novel polyethyleneimine-R8-heparin nanogel for high-efficiency gene delivery in vitro and in vivo

Gene therapy is an efficient and promising approach to treat malignant tumors. However, protecting the nucleic acid from degradation in vivo and efficient delivering it into tumor cells remain challenges that require to be addressed before gene therapy could be applied in clinic. In this study, we p...

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Опубликовано в: :Drug Deliv
Главные авторы: Song, Linjiang, Liang, Xiuqi, Yang, Suleixin, Wang, Ning, He, Tao, Wang, Yan, Zhang, Lan, Wu, Qinjie, Gong, Changyang
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2017
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6058572/
https://ncbi.nlm.nih.gov/pubmed/29265887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2017.1417512
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